IMSI Method

Microinsemination with morphologically selected spermatozoa

the Microinsemination IMSI (Intracytoplasmic Morphologically-Selected Sperm Injection) or else Intracytoplasmic injection of morphologically selected spermatozoa in the egg, is a more sophisticated technique of ICSI Microinsemination, in which a single sperm is injected into the egg.

The difference of the IMSI technique is the overmagnification of the spermatozoa with a special high-resolution electron microscope, which magnifies about 6000x more, In order for the gynecologist to evaluate in every detail the head of the spermatozoa and their internal morphology which is not visible during the usual microinsemination. In this way, the morphology of the spermatozoa is checked with very high fidelity and the choice of those who are only healthy and normal, without genetic damage that can lead to a failed fertilization of the egg with the ICSI method, increases by a high percentage.

Although it remains doubtful whether it can be beneficial in all cases where microinsemination is necessary, the method is recommended for those who have a history of successive failed micro-fertilization attempts or those suffering from sperm dysplasia.

It has been proven that ICSI microinsemination combined with the IMSI technique maximizes the chances of successful fertilization since it increases the percentage of embryos that reach the blastocyst stage and improves the chances of failure of IVF from male infertility problems and a history of miscarriages.

In essence, it is a tool that makes it easier for embryologists to choose the best sperm during microinsemination.

Ioannis A. Sklavounos MD MSC DFFP
Obstetrician Surgeon Gynecologist
Specialists & Retrained in Great Britain
T.Senior Clinical Fellow – Liverpool Woman’s Hospital UK

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Fertility & IVF Center in Maroussi

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